2024
S. Nantogma, H. de Maissin, I. Adelabu, A. Abdurraheem, C. Nelson, N.V. Chukanov, O.G. Salnikov, I.V. Koptyug, S. Lehmkuhl, A.B. Schmidt, S. Appelt, T. Theis, E.Y. Chekmenev, Carbon-13 radiofrequency amplification by stimulated emission of radiation of the hyperpolarized ketone and hemiketal forms of allyl [1-13C]pyruvate, ACS Sens., 2024, 9, 770-780
https://doi.org/10.1021/acssensors.3c02075
S.V. Sviyazov, S.V. Babenko, I.V. Skovpin, L. Kovtunova, N. Chukanov, A.Y. Stakheev, D.B. Burueva, I.V. Koptyug, Manipulating stereoselectivity of parahydrogen addition to acetylene to unravel interconversion of ethylene nuclear spin isomers, Phys. Chem. Chem. Phys., 2024, 26, 7821-7829
https://doi.org/10.1039/D3CP04983C
S. Nantogma, M.R.H. Chowdhury, M.S.H. Kabir, I. Adelabu, S.M. Joshi, A. Samoilenko, H. de Maissin, A.B. Schmidt, P. Nikolaou, Y.A. Chekmenev, O.G. Salnikov, N.V. Chukanov, I.V. Koptyug, B.M. Goodson, E.Y. Chekmenev, MATRESHCA: Microtesla Apparatus for Transfer of Resonance Enhancement of Spin Hyperpolarization via Chemical Exchange and Addition, Anal. Chem., 2024, 96, 4171-4179
https://doi.org/10.1021/acs.analchem.3c05233
N.M. Ariyasingha, M.R.H. Chowdhury, A. Samoilenko, O.G. Salnikov, N.V. Chukanov, L.M. Kovtunova, V.I. Bukhtiyarov, Z. Shi, K. Luo, S. Tan, I.V. Koptyug, B.M. Goodson, E.Y. Chekmenev, Toward lung ventilation imaging using hyperpolarized diethyl ether gas contrast agent, Chem. Eur. J., 2024, e202304071
https://doi.org/10.1002/chem.202304071
S.V. Babenko, S.V. Sviyazov, D.B. Burueva, I.V. Koptyug, Hyperpolarized long-lived spin state of methylene protons of 2-bromoethanol obtained from ethylene with non-equilibrium nuclear spin order, J. Magn. Reson., 2024, 360, 107648
https://doi.org/10.1016/j.jmr.2024.107648
O.G. Salnikov, I.A. Trofimov, Z.T. Bender, A.I. Trepakova, J. Xu, G.L. Wibbels, R.V. Shchepin, I.V. Koptyug, D.A. Barskiy, Parahydrogen-induced polarization of 14N nuclei, Angew. Chem. Int. Ed., 2024, 63, e202402877
https://doi.org/10.1002/anie.202402877
D.B. Burueva, A.V. Bukhtiyarov, I.P. Prosvirin, G.N. Baeva, N.S. Smirnova, I.S. Mashkovsky, V.I. Bukhtiyarov, A.Y. Stakheev, I.V. Koptyug, Rh-based intermetallic Rh-In/SiO2 catalyst for parahydrogen-induced polarization, J. Phys. Chem. C, 2024, 128, 6319-6327
https://doi.org/10.1021/acs.jpcc.4c00651
D.B. Burueva, J. Eills, R. Picazo-Frutos, K.V. Kovtunov, D. Budker, I.V. Koptyug, Detection of Metronidazole and Fampridine by NMR at Zero and Ultralow Magnetic Field, JETP, 2024, 166, 566–570
https://doi.org/10.31857/S0044451024100134
I.A. Trofimov, O.G. Salnikov, A.N. Pravdivtsev, H. de Maissin, A.P. Yi, E.Y. Chekmenev, J.-B. Hovener, A.B. Schmidt, I.V. Koptyug, Through-bond and through-space radiofrequency amplification by stimulated emission of radiation, Commun. Chem., 2024, 7, 235
https://doi.org/10.1038/s42004-024-01313-0
E.V. Pokochueva, E. Kountoupi, M. Janak, D.A. Kuznetsov, I.P. Prosvirin, C. Muller, A. Fedorov, I.V. Koptyug, Implications for the hydrogenation of propyne and propene with parahydrogen due to the in situ transformation of Rh2C to Rh0/C, ChemPhysChem, 2024, 25, e202400270
https://doi.org/10.1002/cphc.202400270
E.V. Pokochueva, D.B. Burueva, O.G. Salnikov, I.V. Koptyug, Branching-Chain Propagation of Parahydrogen-Derived Nuclear Spin Order on a Catalyst Surface, ChemPhysChem, 2024, 25, e202400209
https://doi.org/10.1002/cphc.202400209
O.G. Salnikov, C.D. Assaf, A.P. Yi, S.B. Duckett, E.Y. Chekmenev, J.-B. Hovener, I.V. Koptyug, A.N. Pravdivtsev, Modeling ligand exchange kinetics in iridium complexes catalyzing SABRE nuclear spin hyperpolarization, Anal. Chem., 2024, 96, 11790-11799
https://doi.org/10.1021/acs.analchem.4c01374
S.V. Sviyazov, D.B. Burueva, N.V. Chukanov, I.A. Razumov, E.Y. Chekmenev, I.V. Koptyug, 15N Hyperpolarization of Metronidazole Antibiotic in Aqueous Media using Phase-Separated Signal Amplification by Reversible Exchange with Parahydrogen, J. Phys. Chem. Lett., 2024, 15, 5382–5389
https://doi.org/10.1021/acs.jpclett.4c00875
I.V. Skovpin, D.B. Burueva, L.M. Kovtunova, A.V. Nartova, R.I. Kvon, V.I. Bukhtiyarov, I.V. Koptyug, Scavenger-based immobilized Rh and Ir complexes in hydrogenation of propyne and propene with parahydrogen, Appl. Magn. Reson., 2024, 55, 1275–1291
https://doi.org/10.1007/s00723-024-01660-0
L. Meng, E.V. Pokochueva, Z. Chen, A. Fedorov, F. Vines, F. Illas, I.V. Koptyug, Contrasting metallic (Rh0) and carbidic (2D-Mo2C MXene) surfaces in olefin hydrogenation provides insights on the origin of the pairwise hydrogen addition, ACS Catal., 2024, 14, 12500-12511
https://doi.org/10.1021/acscatal.4c02534
D.B. Burueva, S.V. Sviyazov, N.V. Chukanov, N.R. Mustafin, O.G. Salnikov, E.Y. Chekmenev, K.V. Kovtunov, I.V. Koptyug, Hyperpolarization of [13C]formate using parahydrogen, J. Magn. Reson. Open, 2024, 21, 100176
https://doi.org/10.1016/j.jmro.2024.100176
N.M. Ariyasingha, A. Samoilenko, M. R. H. Chowdhury, S. Nantogma, C. Oladun, J. R. Birchall, T. Bawardi, O.G. Salnikov, L.M. Kovtunova, V.I. Bukhtiyarov, Z. Shi, K. Luo, S. Tan, I.V. Koptyug, B.M. Goodson, E.Y. Chekmenev, Developing hyperpolarized butane gas for ventilation lung imaging, Chem. Biomed. Imaging, 2024, 2, 698-710
https://doi.org/10.1021/cbmi.4c00041
A.P. Yi, O.G. Salnikov, D.B. Burueva, N.V. Chukanov, E.Y. Chekmenev, I.V. Koptyug, Solvent Effects in Hyperpolarization of 15N Nuclei in [15N3]Metronidazole and [15N3]Nimorazole Antibiotics via SABRE-SHEATH, Analysis & Sensing, 2024, 4, e202400045
https://doi.org/10.1002/anse.202400045
M.R.H. Chowdhury, C. Oladun, N.M. Ariyasingha, A. Samoilenko, T. Bawardi, D.B. Burueva, O.G. Salnikov, L.M. Kovtunova, V.I. Bukhtiyarov, Z. Shi, K. Luo, S. Tan, J.G. Gelovani, I.V. Koptyug, B.M. Goodson, E.Y. Chekmenev, Rapid lung ventilation MRI using parahydrogen-induced polarization of propane gas, Analyst, 2024, 149, 5832–5842
https://doi.org/10.1039/d4an01029a
D.B. Burueva, I.V. Skovpin, L.M. Kovtunova, E.S. Kononenko, V.I. Bukhtiyarov, I.V. Koptyug, Butynes Hydrogenation with Parahydrogen over Immobilized Iridium Catalyst, Kinet. Catal., 2024, 65, 754–762
https://doi.org/10.1134/S0023158424602705
C.D. Assaf, X. Gui, O.G. Salnikov, A. Brahms, N.V. Chukanov, I.V. Skovpin, E.Y. Chekmenev, R. Herges, S.B. Duckett, I.V. Koptyug, K. Buckenmaier, R. Körber, M. Plaumann, A.A. Auer, J.-B. Hövener, A.N. Pravdivtsev, Analysis of chemical exchange in iridium N-heterocyclic carbene complexes using heteronuclear parahydrogen-enhanced NMR, Commun. Chem., 2024, 7, 286
https://doi.org/10.1038/s42004-024-01376-z
A.V. Nartova, R.I. Kvon, L.M. Kovtunova, A. M. Dmitrachkov, I.V. Skovpin, V.I. Bukhtiyarov, XPS study of the stability variations of [M(COD)Cl]2 (M = Ir, Rh) complexes anchored on modified silica in reactions of spin-selective hydrogenation of unsaturated hydrocarbons by parahydrogen, Kinet. Catal., 2024, 65, 214–223
https://doi.org/10.31857/S0453881124020096
2023
I. Koptyug, K. Kovtunov, A. Svyatova. "Magnetic resonance imaging (MRI)", in: Springer handbook of advanced catalyst characterization, I.E. Wachs, M.A. Banares, eds. 2023, Springer International Publishing:Cham, 849-867
https://doi.org/10.1007/978-3-031-07125-6_37E.V. Pokochueva,
A.I. Svyatova, D.B. Burueva, I.V. Koptyug, Chemistry of nuclear spin isomers of the molecules: from the past of the
Universe to emerging technologies, Russ. Chem. Bull., 2023, 72, 1-19
https://doi.org/10.1007/s11172-023-3711-7
B.E. Kidd, M.E. Gemeinhardt, J.A. Mashni, J.L. Gesiorski, L.B. Bales, M.N. Limbach, R.V. Shchepin, K.V. Kovtunov, I.V. Koptyug, E.Y. Chekmenev, B.M. Goodson, Hyperpolarizing DNA nucleobases via NMR signal amplification by reversible exchange, Molecules, 2023, 28, 1198
https://doi.org/10.3390/molecules28031198
J. Eills, D. Budker, S. Cavagnero, E.Y. Chekmenev, S.J. Elliott, S. Jannin, A. Lesage, J. Matysik, T. Meersmann, T. Prisner, J.A. Reimer, H. Yang, I.V. Koptyug. Spin Hyperpolarization in Modern Magnetic Resonance, Chem. Rev., 2023, 123, 1417-1551
https://pubs.acs.org/doi/10.1021/acs.chemrev.2c00534
J. Eills, R. Picazo-Frutos, D.B. Burueva, L.M. Kovtunova, M. Azagra, I. Marco-Rius, D. Budker, I.V. Koptyug, Combined homogeneous and heterogeneous hydrogenation to yield catalyst-free solutions of parahydrogen-hyperpolarized [1-13C]succinate, Chem. Commun., 2023, 59, 9509-9512
https://doi.org/10.1039/D3CC01803B
I.V. Skovpin, A.I. Trepakova, L.M. Kovtunova, I.V. Koptyug, Spatially resolved NMR spectroscopy for operando studies of heterogeneous hydrogenation with parahydrogen, Appl. Magn. Reson., 2023, 54, 1271-1282
https://doi.org/10.1007/s00723-023-01587-y
D.A. Barskiy, J.W. Blanchard, D. Budker, Q. Stern, J. Eills, S.J. Elliott, R. Picazo-Frutos, A. Garcon, S. Jannin, I.V. Koptyug, Possible applications of dissolution dynamic nuclear polarization in conjunction with zero- to ultralow-field nuclear magnetic resonance, Appl. Magn. Reson., 2023, 54, 1221-1240
https://doi.org/10.1007/s00723-023-01592-1
O.G. Salnikov, D.B. Burueva, I.V. Skovpin, I.V. Koptyug, Parahydrogen-based NMR signal amplification by reversible exchange (SABRE): recent advances and applications, Mendeleev Commun., 2023, 33, 583-596
https://doi.org/10.1016/j.mencom.2023.09.001
N.M. Ariyasingha, A. Samoilenko, J.R. Birchall, M.R.H. Chowdhury, O.G. Salnikov, L.M. Kovtunova, V.I. Bukhtiyarov, D.C. Zhu, C. Qian, M. Bradley, J.G. Gelovani, I.V. Koptyug, B.M. Goodson, E.Y. Chekmenev, Ultra-low-cost disposable hand-held clinical-scale propane gas hyperpolarizer for pulmonary magnetic resonance imaging sensing, ACS Sens., 2023, 8, 3845-3854
https://doi.org/10.1021/acssensors.3c01369
I.V. Skovpin, S.V. Sviyazov, D.B. Burueva, L.M. Kovtunova, A.V. Nartova, R.I. Kvon, V.I. Bukhtiyarov, I.V. Koptyug, Nonequilibrium nuclear spin states of ethylene during acetylene hydrogenation with parahydrogen over immobilized iridium complexes, Doklady Phys. Chem., 2023, 512, 149-157
https://doi.org/10.1134/S0012501623600237
N.M. Ariyasingha, S. Nantogma, A. Samoilenko, O.G. Salnikov, N.V. Chukanov, L.M. Kovtunova, I.V. Koptyug, E.Y. Chekmenev, Efficient polarization redistribution in hyperpolarized 1-D-propane produced via pairwise parahydrogen addition, J. Magn. Reson. Open, 2023, 16-17, 100135
https://doi.org/10.1016/j.jmro.2023.100135
A.V. Nartova, R.I. Kvon, L.M. Kovtunova, I.V. Skovpin, I.V. Koptyug, V.I. Bukhtiyarov, XPS and HR TEM elucidation of the diversity of titania-supported single-site Ir catalyst performance in spin-selective propene hydrogenation, Int. J. Mol. Sci., 2023, 24, 15643
https://doi.org/10.3390/ijms242115643
M.Yu. Smirnov, L.M. Kovtunova, A.V. Kalinkin, I.V. Skovpin, I.V. Koptyug, V.I. Bukhtiyarov, XPS study of the synthesis of single-site catalysts based on Ir(I) and Rh(I) complexes immobilized on the SiO2 surface using a P-containing linker, Kinet. Catal., 2023, 64, 895-908
https://doi.org/10.1134/S0023158423060150
O.G. Salnikov, E.V. Pokochueva, D.B. Burueva, L.M. Kovtunova, K.V. Kovtunov, I.V. Koptyug, Parahydrogen-induced polarization in gas-phase heterogeneous hydrogenation of epoxides, J. Phys. Chem. C, 2023, 127, 23634-23644
https://doi.org/10.1021/acs.jpcc.3c05059
2022
A.I. Trepakova, I.V. Skovpin, N.V. Chukanov, O.G. Salnikov, E.Y. Chekmenev, A.N. Pravdivtsev, J.-B. Hövener, I.V. Koptyug. Subsecond three-dimensional nitrogen-15 magnetic resonance imaging facilitated by parahydrogen-based hyperpolarization, J. Phys. Chem. Lett., 2022, 13, 10253–10260
https://doi.org/10.1021/acs.jpclett.2c02705
O.G. Salnikov, I.A. Trofimov, A.N. Pravdivtsev, K. Them, J.-B. Hövener, E.Y. Chekmenev, I.V. Koptyug, Through-space multinuclear magnetic resonance signal enhancement induced by parahydrogen and radiofrequency amplification by stimulated emission of radiation, Anal. Chem., 2022, 94, 15010–15017
https://doi.org/10.1021/acs.analchem.2c02929
E.S. Kononenko, A.I. Svyatova, I.V. Skovpin, L.M. Kovtunova, E. Yu. Gerasimov, I.V. Koptyug, Getting the most out of parahydrogen-induced signal enhancement for MRI of reacting heterogeneous systems, J. Phys. Chem. C, 2022, 126, 14914–14921
https://doi.org/10.1021/acs.jpcc.2c05218
I.V. Skovpin, L.M. Kovtunova, A.V. Nartova, R.I. Kvon, V.I. Bukhtiyarov, I.V. Koptyug, Anchored complexes of rhodium and iridium in the hydrogenation of alkynes and olefins with parahydrogen, Catal. Sci. Technol., 2022, 12, 3247–3253
https://doi.org/10.1039/D1CY02258J
A.N. Pravdivtsev, D.A. Barskiy, J.-B. Hövener, I.V. Koptyug, Symmetry constraints on spin order transfer in parahydrogen-induced polarization (PHIP), Symmetry, 2022, 14, 530
https://doi.org/10.3390/sym14030530
I.V. Koptyug, Q. Stern, S. Jannin, S.J. Elliot, Frozen water NMR lineshape analysis enables absolute polarization quantification, Phys. Chem. Chem. Phys., 2022, 24, 5956–5964
https://doi.org/10.1039/D1CP05127J
O.G. Salnikov, D.B. Burueva, L.M. Kovtunova, V.I. Bukhtiyarov, K.V. Kovtunov, I.V. Koptyug, Mechanisms of methylenecyclobutane hydrogenation over supported metal catalysts studied by parahydrogen-induced polarization technique, ChemPhysChem, 2022, 23, e202200072
https://doi.org/10.1002/cphc.202200072
A.B. Schmidt, C. R. Bowers, K. Buckenmaier, E.Y. Chekmenev, H. de Maissin, J. Eills, F. Ellermann, S. Glöggler, J.W. Gordon, S. Knecht, I.V. Koptyug, J. Kuhn, A.N. Pravdivtsev, F. Reineri, T. Theis, K. Them, J.-B. Hövener, Instrumentation for hydrogenative parahydrogen-based hyperpolarization techniques, Anal. Chem., 2022, 94, 479–502
https://doi.org/10.1021/acs.analchem.1c04863
A. Parastaev, V. Muravev, E. Huertas Osta, T.F. Kimpel, J.F.M. Simons, A.J.F. van Hoof, E. Uslamin, L. Zhang, J.J.C. Struijs, D.B. Burueva, E.V. Pokochueva, K.V. Kovtunov, I.V. Koptyug, I.J. Villar-Garcia, C. Escudero, T. Altantzis, P. Liu, A. Béché, S. Bals, N. Kosinov, E.J.M. Hensen, Breaking structure sensitivity in CO2 hydrogenation by tuning metal–oxide interfaces in supported cobalt nanoparticles, Nat. Catal., 2022, 5, 1051–1060
https://doi.org/10.1038/s41929-022-00874-4
D.B. Burueva, V.P. Kozinenko, S.V. Sviyazov, L.M. Kovtunova, V.I. Bukhtiyarov, E.Y. Chekmenev, O.G. Salnikov, K.V. Kovtunov, I.V. Koptyug, Gas-phase NMR of hyperpolarized propane with 1H-to-13C polarization transfer by PH-INEPT, Appl. Magn. Reson., 2022, 53, 653–669
https://doi.org/10.1007/s00723-021-01377-4
O.Yu. Selyutina, S.V. Babenko, A.I. Kruppa, T.V. Leshina, N.E. Polyakov, Photostabilization of ketoprofen by inclusion in glycyrrhizin micelles and gel nanoparticles, New J. Chem., 2022, 46, 17865–17873
https://doi.org/10.1039/D2NJ02553A
A.A. Ageeva, A.I. Kruppa, I.M. Magin, S.V. Babenko, T.V. Leshina, New aspects of the antioxidant activity of glycyrrhizin revealed by the CIDNP technique, Antioxidants, 2022, 11, 1591
https://doi.org/10.3390/antiox11081591
2021
O.G. Salnikov, N.V. Chukanov, A. Svyatova, I.A. Trofimov, M.S.H. Kabir, J.G. Gelovani, K.V. Kovtunov, I.V. Koptyug, E.Y. Chekmenev. 15N NMR hyperpolarization of radiosensitizing antibiotic nimorazole via reversible parahydrogen exchange in microtesla magnetic fields, Angew. Chem. Int. Ed., 2021, 60, 2406-2413
https://doi.org/10.1002/anie.202011698
A.N. Pravdivtsev, G. Buntkowsky, S.B. Duckett, I.V. Koptyug, J.-B. Hövener. Parahydrogen-induced polarization of amino acids, Angew. Chem. Int. Ed., 2021
https://doi.org/10.1002/anie.202100109
B. Joalland, N.M. Ariyasingha, H.R. Younes, S. Nantogma, O.G. Salnikov, N.V. Chukanov, K.V. Kovtunov, I.V. Koptyug, J.G. Gelovani, E.Y. Chekmenev. Low-flammable parahydrogen-polarized MRI contrast agents, Chem. Eur. J., 2021, 27, 2774-2781
https://doi.org/10.1002/chem.202004168
E.Y. Chekmenev, B.M. Goodson, V.I. Bukhtiyarov, I.V. Koptyug. Bridging the gap: from homogeneous to heterogeneous PHIP and beyond, ChemPhysChem, 2021, 22,710-715
https://doi.org/10.1002/cphc.202001031
N.V. Chukanov, O.G. Salnikov, I.A. Trofimov, M.S.H. Kabir, K.V. Kovtunov, I.V. Koptyug, E.Y. Chekmenev. Synthesis and 15N NMR signal amplification by reversible exchange of [15N]Dalfampridine at microtesla magnetic fields, ChemPhysChem, 2021, 22, 960-967
https://doi.org/10.1002/cphc.202100109
A. Svyatova, V.P. Kozinenko, N.V. Chukanov, D.B. Burueva, E.Y. Chekmenev, Y.-W. Chen, D.W. Hwang, K.V. Kovtunov, I.V. Koptyug. PHIP hyperpolarized [1-13C]pyruvate and [1-13C]acetate esters via PH-INEPT polarization transfer monitored by 13C NMR and MRI, Sci. Rep., 2021, 11, 5646
https://doi.org/10.1038/s41598-021-85136-2
O.G. Salnikov, A. Svyatova, L.M. Kovtunova, N.V. Chukanov, V.I. Bukhtiyarov, K.V. Kovtunov, E.Y. Chekmenev, I.V. Koptyug. Heterogeneous parahydrogen-induced polarization of diethyl ether for magnetic resonance imaging applications, Chem. Eur. J., 2021, 27, 1316-1322
https://doi.org/10.1002/chem.202003638
E. Pokochueva, D. Burueva, L. Kovtunova, A. Bukhtiyarov, A. Gladky, K.V. Kovtunov, I.V. Koptyug, V. Bukhtiyarov. Mechanistic in situ investigation of heterogeneous hydrogenation over Rh/TiO2 catalysts: selectivity, pairwise route, catalyst nature, Faraday Discuss., 2021, 229, 161-175
https://doi.org/10.1039/C9FD00138G
2020
P. Holtkamp, J. Schwabedissen, B. Neumann, G. Stammler, I. Koptyug, V. Zhivonitko, N.W. Mitzel. A zwitterionic phosphonium stannate(II) via hydrogen splitting by a Sn/P frustrated lewis-pair and reductive elimination, Chem. Eur. J., 2020, 26, 17381-17385
https://doi.org/10.1002/chem.202004425
M.A. Naeem, D.B. Burueva, P.M. Abdala, N.S. Bushkov, D. Stoian, A.V. Bukhtiyarov, I.P. Prosvirin, V.I. Bukhtiyarov, K.V. Kovtunov, I.V. Koptyug, A. Fedorov, C.R. Muller. Deciphering the nature of Ru sites in reductively exsolved oxides with electronic and geometric metal-support interactions, J. Phys. Chem. C, 2020, 124, 25299-25307
https://doi.org/10.1021/acs.jpcc.0c07203
J.R. Birchall, R.K. Irwin, P. Nikolaou, E.V. Pokochueva, K.V. Kovtunov, I.V. Koptyug, M.J. Barlow, B.M. Goodson, E.Y. Chekmenev. Pilot multi-site quality assurance study of batch-mode clinical-scale automated xenon-129 hyperpolarizers, J. Magn. Reson., 2020, 316, 106755
https://doi.org/10.1016/j.jmr.2020.106755
N.M. Ariyasingha, B. Joalland, H.R. Younes, O.G. Salnikov, N.V. Chukanov, K.V. Kovtunov, L.M. Kovtunova, V.I. Bukhtiyarov, I.V. Koptyug, J.G. Gelovani, E.Y. Chekmenev. Parahydrogen-induced polarization of diethyl ether anesthetic, Chem. Eur. J., 2020, 26, 13621-13626
https://doi.org/10.1002/chem.202002528
D.B. Burueva, E.V. Pokochueva, X. Wang, M. Filkins, A. Svyatova, S.P. Rigby, C. Wang, G.E. Pavlovskaya, K.V. Kovtunov, T. Meersmann, I.V. Koptyug. In situ monitoring of heterogeneous catalytic hydrogenation via 129Xe NMR spectroscopy and proton MRI, ACS Catal., 2020, 10, 1417-1422
https://doi.org/10.1021/acscatal.9b05000
D.B. Burueva, J. Eills, J.W. Blanchard, A. Garcon, R. Picazo-Frutos, K.V. Kovtunov, I.V. Koptyug, D. Budker. Chemical reaction monitoring using zero-field nuclear magnetic resonance enables study of heterogeneous samples in metal containers, Angew. Chem. Int. Ed., 2020, 59, 17026-17032
https://doi.org/10.1002/anie.202006266
J.R. Birchall, P. Nikolaou, R.K. Irwin, M.J. Barlow, K. Ranta, A.M. Coffey, B.M. Goodson, E.V. Pokochueva, K.V. Kovtunov, I.V. Koptyug, E.Y. Chekmenev. Helium-rich mixtures for improved batch-mode clinical-scale spin-exchange optical pumping of xenon-129, J. Magn. Reson., 2020, 315, 106739
https://doi.org/10.1016/j.jmr.2020.106739
J.R. Birchall, M.S.H. Kabir, O.G. Salnikov, N.V. Chukanov, A. Svyatova, K.V. Kovtunov, I.V. Koptyug, J.G. Gelovani, B.M. Goodson, W. Pham, E.Y. Chekmenev. Quantifying the effects of quadrupolar sinks via 15N relaxation dynamics in metronidazoles hyperpolarized via SABRE-SHEATH, Chem. Commun., 2020, 56, 9098-9101
https://doi.org/10.1039/D0CC03994B
A. Svyatova, E.S. Kononenko, K.V. Kovtunov, D. Lebedev, E.Y. Gerasimov, A. Bukhtiyarov, I. Prosvirin, V. Bukhtiyarov, C.R. Muller, A. Fedorov, I.V. Koptyug. Spatially resolved NMR spectroscopy of heterogeneous gas phase hydrogenation of 1,3-butadiene with parahydrogen, Catal. Sci. Technol., 2020, 10, 99-104
https://doi.org/10.1039/C9CY02100K
K.V. Kovtunov, O.G. Salnikov, I.V. Skovpin, N.V. Chukanov, D.B. Burueva, I.V. Koptyug. Catalytic hydrogenation with parahydrogen: a bridge from homogeneous to heterogeneous catalysis, Pure & Appl. Chem., 2020, 92, 1029-1046
https://doi.org/10.1515/pac-2020-0203
B. Joalland, A. Schmidt, M.S.H. Kabir, N.V. Chukanov, K.V. Kovtunov, I.V. Koptyug, J. Hennig, J.-B. Hovener, E.Y. Chekmenev. Pulse-programmable magnetic field sweeping of parahydrogen-induced polarization by side arm hydrogenation, Anal. Chem., 2020, 92, 1340-1345
https://doi.org/10.1021/acs.analchem.9b04501
D.B. Burueva, A.A. Smirnov, O.A. Bulavchenko, I.P. Prosvirin, E.Y. Gerasimov, V.A. Yakovlev, K.V. Kovtunov, I.V. Koptyug. Pairwise parahydrogen addition over molybdenum carbide catalysts, Topics in Catalysis, 2020, 63, 2-11
https://doi.org/10.1007/s11244-019-01211-z
K.V. Kovtunov, I.V. Koptyug, M. Fekete, S.B. Duckett, T. Theis, B. Joalland, E.Y. Chekmenev. Parahydrogen-induced hyperpolarization of gases, Angew. Chem. Int. Ed., 2020, 59, 17788-17797
https://doi.org/10.1002/anie.201915306
2019
P. Jurt, O.G. Salnikov, T.L. Gianetti, N.V. Chukanov, M.G. Baker, G. Le Corre, J.E. Borger, R. Verel, S. Gauthier, O. Fuhr, K.V. Kovtunov, A. Fedorov, D. Fenske, I.V. Koptyug, H. Grützmacher, Low-valent Homobimetallic Rh Complexes: Influence of Ligands on the Structure and the Intramolecular Reactivity of Rh–H Intermediates, Chem. Sci., 2019, 10, 7937-7945.
https://pubs.rsc.org/en/content/articlelanding/2019/sc/c9sc02683e
A. Svyatova, I. V. Skovpin, N. V. Chukanov, K. V. Kovtunov, E. Y. Chekmenev, A. N. Pravdivtsev, J.-B. Hovener, I. V. Koptyug. 15N MRI of SLIC-SABRE hyperpolarized 15N- labelled pyridine and nicotinamide. In: Chem. Eur. J., 2019. https://doi.org/10.1002/chem.201900430
R. V Shchepin, J. R. Birchall, N. V. Chukanov, K. V. Kovtunov, I. V. Koptyug, T. Theis, W. S. Warren, J. G. Gelovani, B. M. Goodson, S. Shokouhi, M. S. Rosen, Y.-F. Yen, W. Pham, E. Y. Chekmenev. Hyperpolarizing Concentrated Metronidazole 15NO2 Group Over Six Chemical Bonds with More Than 15% Polarization and 20 Minute Lifetime. In: Chem. Eur. J., 2019. https://doi.org/10.1002/chem.201901192
N. M. Ariyasingha, O. G. Salnikov, K. V. Kovtunov, L. M. Kovtunova, V. I. Bukhtiyarov, B. M. Goodson, M. S. Rosen, I. V. Koptyug, J. G. Gelovani, E. Y. Chekmenev. Relaxation Dynamics of Nuclear Long-Lived Spin States in Propane and Propane-d6 Hyperpolarized by Parahydrogen. In: JPCC, 2019. https://doi.org/10.1021/acs.jpcc.9b01538
N. V. Chukanov, B. E. Kidd, L. M. Kovtunova, V. I. Bukhtiyarov, R. V. Shchepin, E. Y. Chekmenev, B. M. Goodson, K V. Kovtunov, I. V. Koptyug. A versatile synthetic route to the preparation of 15N heterocycles. J. Label. Compd. Radiopharm. 2019;1–11. https://doi.org/10.1002/jlcr.3699
O. G. Salnikov, P. Nikolaou, N. M. Ariyasingha, K. V. Kovtunov , I. V. Koptyug, E. Y. Chekmenev. Clinical-Scale Batch-Mode Production of Hyperpolarized Propane Gas for MRI. Anal Chem, 2019, 91, 4741-4746. https://doi.org/10.1021/acs.analchem.9b00259
D. B. Burueva, L. M. Kovtunova, V. I. Bukhtiyarov, K. V. Kovtunov, I. V. Koptyug. Single‐Site Heterogeneous Catalysts: From Synthesis to NMR Signal Enhancement. In: Chem. Eur. J., 2019, 25, 1420-1431. http://dx.doi.org/10.1002/chem.201803515
V. V. Zhivonitko, J. Bresien, A. Schulz, I. V. Koptyug. Parahydrogen-induced polarization with a metal-free P–P biradicaloid. In: Phys. Chem. Chem. Phys., 2019, 21, 5890-5893. http://dx.doi.org/10.1039/C8CP07625A
A. I. Svyatova, K. V. Kovtunov, I. V. Koptyug. Magnetic resonance imaging of catalytically relevant processes. In: Rev. Chem. Eng., 2019, 1-27. http://dx.doi.org/10.1515/revce-2018-0035
K. V. Kovtunov, D. Lebedev, A. Svyatova, E. V. Pokochueva, Igor P. Prosvirin, E. Y. Gerasimov, V. I. Bukhtiyarov, C. R. Müller, A. Fedorov, I. V. Koptyug. Robust In Situ Magnetic Resonance Imaging of Heterogeneous Catalytic Hydrogenation with and without Hyperpolarization. In: ChemCatChem, 11, 969-973. http://dx.doi.org/10.1002/cctc.201801820
2018
Zhivonitko V.V., Svyatova A.I., Kovtunov K.V., Koptyug I.V. Recent MRI studies on heterogeneous catalysis. In: Annu. Rep. NMR Spectrosc., 2018, 95, 83-145. ; Ed. G. A. Webb. Elsevier (Academic Press), London, UK. 200 pp. Chapter 2, pp 83-145. ISBN 978-0-08-102668-7; ISSN 0066-4103. http://dx.doi.org/10.1016/bs.arnmr.2018.06.001
Bukhtiyarov A.V., Burueva D.B., Prosvirin I.P., Klyushin A.Y., Panafidin M.A., Kovtunov K.V., Bukhtiyarov V.I., Koptyug I.V. / Bimetallic Pd-Au/HOPG catalysts: from composition to pairwise parahydrogen addition selectivity / J. Phys. Chem., C, 2018, 122, 18588-18595. http://dx.doi.org/10.1021/acs.jpcc.8b06281
Burueva D.B., Kovtunov K.V., Bukhtiyarov A.V., Barskiy D.A., Prosvirin I.P., Mashkovsky I.S., Baeva G.N., Bukhtiyarov V.I., Stakheev A.Y., Koptyug I.V. / Selective single-site Pd-In hydrogenation catalyst for production of enhanced magnetic resonance signals using parahydrogen / Chem. Eur. J., 2018, 24, 2547-2553. http://dx.doi.org/10.1002/chem.201705644
Chukanov N.V., Salnikov O.G., Shchepin R.V., Svyatova A., Kovtunov K.V., Koptyug I.V., Chekmenev E.Y. / 19F Hyperpolarization of 15N-3-19F-Pyridine Via Signal Amplification by Reversible Exchange / J. Phys. Chem. C, 2018, 122, 23002-23010. http://dx.doi.org/10.1021/acs.jpcc.8b06654
Chukanov N.V., Salnikov O.G., Shchepin R.V., Kovtunov K.V., Koptyug I.V., Chekmenev E.Y. / Synthesis of unsaturated precursors for parahydrogen-induced polarization and molecular imaging of 1-13C-acetates and 1-13C-pyruvates via side arm hydrogenation / ACS Omega, 2018, 3, 6673-6682.; http://dx.doi.org/10.1021/acsomega.8b00983
Kidd B.E., Gesiorski J.L., Gemeinhardt M.E., Shchepin R.V., Kovtunov K.V., Koptyug I.V., Chekmenev E.Y., Goodson B.M. / Facile removal of homogeneous SABRE catalysts for purifying hyperpolarized metronidazole, a potential hypoxia sensor / J. Phys. Chem. C, 2018, 122, 16848-16852.; http://dx.doi.org/10.1021/acs.jpcc.8b05758
Kovtunov K. V., Pokochueva E. V., Salnikov O. G., Cousin S. F., Kurzbach D., Vuichoud B., Jannin S., Chekmenev E. Y., Goodson B. M., Barskiy D. A., Koptyug I. V. / Hyperpolarized NMR: d-DNP, PHIP, and SABRE / Chem. Asian J., 2018, 13, 1857-1871. http://dx.doi.org/10.1002/asia.201800551
Pravdivtsev A. N., Skovpin I. V., Svyatova A. I., Chukanov N. V., Kovtunova L. M., Bukhtiyarov V. I., Chekmenev E. Y., Kovtunov K. V., Koptyug I. V., Hovener J.-B. / Chemical Exchange Reaction Effect on Polarization Transfer Efficiency in SLIC-SABRE / J. Phys. Chem. A, 2018, 122 (46), 9107–9114. http://dx.doi.org/10.1021/acs.jpca.8b07163
Salnikov O., Kovtunov K., Nikolaou P., Kovtunova L., Bukhtiyarov V.I., Koptyug I.V., Chekmenev E.Y. / Heterogeneous parahydrogen pairwise addition to cyclopropane / ChemPhysChem, 2018, 19, 2621-2626. http://dx.doi.org/10.1002/cphc.201800690
Salnikov O.G., Kovtunova L.M., Skovpin I.V., Bukhtiyarov V.I., Kovtunov K.V., Koptyug I.V. / Mechanistic insight into heterogeneous hydrogenation of furan derivatives with the use of parahydrogen / ChemCatChem, 2018, 10, 1178-1183. http://dx.doi.org/10.1002/cctc.201701653
Salnikov O.G., Shchepin R.V., Chukanov N.V., Jaigirdar L., Pham W., Kovtunov K.V., Koptyug I.V., Chekmenev E.Y. / The effects of deuteration of 13C-enriched phospholactate on the efficiency of parahydrogen-induced polarization using magnetic field cycling / J. Phys. Chem. C, 2018, 122, 24740-24749. http://dx.doi.org/10.1021/acs.jpcc.8b07365
Selent A., Zhivonitko V.V., Koptyug I.V., Telkki V.-V. / Quantifying the adsorption of flowing gas mixtures in porous materials by remote detection NMR / Microporous Mesoporous Mater., 2018, 269, 148-151. http://dx.doi.org/10.1016/j.micromeso.2017.05.040
Sorochkina K., Zhivonitko V.V., Chernichenko K., Telkki V.-V., Repo T., Koptyug I.V. / Spontaneous 15N nuclear spin hyperpolarization in metal-free activation of parahydrogen by molecular tweezers / J. Phys. Chem. Lett., 2018, 9, 903-907. http://dx.doi.org/10.1021/acs.jpclett.7b03433
Zhivonitko V.V., Skovpin I.V., Szeto K.C., Taoufik M., Koptyug I.V. / Parahydrogen-induced polarization study of silica-supported vanadium oxo organometallic catalyst / J. Phys. Chem. C, 2018, 122, 4891-4900. http://dx.doi.org/10.1021/acs.jpcc.7b12069
2017
Babailov S., Akulov A., Moshkin M., Koptyug I. / Prospects of paramagnetic lanthanide complexes for magnetic resonance imaging, local thermosensing / J. Phys. Conf. Ser., 2017, 886, 012003; http://dx.doi.org/10.1088/1742-6596/886/1/012003
Bales L.B., Kovtunov K.V., Barskiy D.A., Shchepin R.V., Coffey A.M., Kovtunova L.M., Bukhtiyarov A.V., Feldman M.A., Bukhtiyarov V.I., Chekmenev E.Y., Koptyug I.V., Goodson B.M. / Aqueous, heterogeneous para-hydrogen-induced 15N polarization / J. Phys. Chem. C, 2017, 121, 15304-15309; http://dx.doi.org/10.1021/acs.jpcc.7b05912
Barskiy D.A., Coffey A.M., Nikolaou P., Mikhaylov D.M., Goodson B.M., Branca R.T., Lu G.J., Shapiro M.G., Telkki V.-V., Zhivonitko V.V., Koptyug I.V., Salnikov O.G., Kovtunov K.V., Bukhtiyarov V.I., Rosen M.S., Barlow M.J., Safavi S., Hall I.P., Schröder L., Chekmenev E.Y. / NMR Hyperpolarization Techniques of Gases / Chem.-A Eur. J,. 2017, 23, 725-751, http://dx.doi.org/10.1002/chem.201603884
Barskiy D.A., Kovtunov K.V., Gerasimov E.Y., Phipps M.A., Salnikov O.G., Coffey A.M., Kovtunova L.M., Prosvirin I.P., Bukhtiyarov V.I., Koptyug I.V., Chekmenev E.Y. / 2D mapping of NMR signal enhancement and relaxation for heterogeneously hyperpolarized propane gas / J. Phys. Chem. C, 2017, 121, 10038-10046; http://dx.doi.org/10.1021/acs.jpcc.7b02506
Barskiy D.A., Salnikov O.G., Romanov A.S., Feldman M.A., Coffey A.M., Kovtunov K.V., Koptyug I.V., Chekmenev E.Y. / NMR spin-lock induced crossing (SLIC) dispersion and long-lived spin states of gaseous propane at low magnetic field (0.05 T) / J. Magn. Reson., 2017, 276, 78-85; http://dx.doi.org/10.1016/j.jmr.2017.01.014
Burueva D.B., Romanov A.S., Salnikov O.G., Zhivonitko V.V., Chen Y.-W., Barskiy D.A., Chekmenev E.Y., Hwang D.W.-H., Kovtunov K.V., Koptyug I.V. / Extending the lifetime of hyperpolarized propane gas via reversible dissolution / J. Phys. Chem. C, 2017, 121, 4481-4487; http://dx.doi.org/10.1021/acs.jpcc.7b00509
Delley M.F., Silaghi M.-C., Nunez-Zarur F., Kovtunov K.V., Salnikov O.G., Estes D.P., Koptyug I.V., Comas-Vives A., Coperet C. / X-H bond activation on Cr(III),O sites (X = R, H): key steps in dehydrogenation and hydrogenation processes / Organomet., 2017, 36, 234-244; http://dx.doi.org/10.1021/acs.organomet.6b00744
Kovtunov K.V., Kidd B.E., Salnikov O.G., Bales L.B., Gemeinhardt M.E., Gesiorski J., Shchepin R.V., Chekmenev E.Y., Goodson B.M., Koptyug I.V. / Imaging of biomolecular NMR signals amplified by reversible exchange with parahydrogen inside an MRI scanner / J. Phys. Chem. C, 2017, 121, 25994-25999; http://dx.doi.org/10.1021/acs.jpcc.7b10549
Kovtunov K.V., Kovtunova L.M., Gemeinhardt M.E., Bukhtiyarov A.V., Gesiorski J., Bukhtiyarov V.I., Chekmenev E.Y., Koptyug I.V., Goodson B. / Heterogeneous microtesla SABRE enhancement of 15N NMR signals / Angew. Chem. Int. Ed., 2017, 56, 10433-10437; http://dx.doi.org/10.1002/anie.201705014
Lisitskiy V.A., Khan H., Popova T.V., Chubarov A.S., Zakharova O.D., Akulov A.E., Shevelev O.B., Zavjalov E.L., Koptyug I.V., Moshkin M.P., Silnikov V.N., Ahmad S., Godovikova T.S. / Multifunctional human serum albumin-therapeutic nucleotide conjugate with redox and pH-sensitive drug release mechanism for cancer theranostics / Bioorg. Med. Chem. Lett., 2017, 27, 3925-3930; http://dx.doi.org/10.1016/j.bmcl.2017.05.084
Rontu V., Selent A., Zhivonitko V., Scotti G., Koptyug I., Telkki V.-V., Franssila S. / Efficient catalytic microreactors with atomic layer deposited platinum nanoparticles on oxide support / Chem. Eur. J., 2017, 23, 16835-16842; http://dx.doi.org/10.1002/chem.201703391
Salnikov O.G., Burueva D.B., Gerasimov E.Y., Bukhtiyarov A.V., Khudorozhkov A.K., Prosvirin I.P., Kovtunova L.M., Barskiy D.A., Bukhtiyarov V.I., Kovtunov K.V., Koptyug I.V. / The effect of oxidative and reductive treatments of titania-supported metal catalysts on the pairwise hydrogen addition to unsaturated hydrocarbons / Catalysis Today, 2017, 283, 82–88; http://dx.doi.org/10.1016/j.cattod.2016.02.030
Salnikov O.G., Liu H.-J., Fedorov A., Burueva D., Kovtunov K.V., Coperet C., Koptyug I.V. / Pairwise hydrogen addition in the selective semihydrogenation of alkynes on silica-supported Cu catalysts / Chem. Sci., 2017, 8, 2426-2430; http://dx.doi.org/10.1039/C6SC05276B
Shchepin R.V., Barskiy D.A., Coffey A.M., Feldman M.A., Kovtunova L.M., Bukhtiyarov V.I., Kovtunov K.V., Goodson B.M., Koptyug I.V., Chekmenev E.Y. / Robust imidazole-15N2 synthesis for high-resolution low-field (0.05 T) 15N hyperpolarized NMR spectroscopy / ChemistrySelect, 2017, 2, 4478-4483; http://dx.doi.org/10.1002/slct.201700718
Skovpin I.V., Zhivonitko V.V., Prosvirin I.P., Khabibulin D.F., Koptyug I.V. / Gas-Phase Hydrogenation with Parahydrogen Over Immobilized Vaska’s Complex // Z. Phys. Chemie, 2017, 231 (3), 575–592. http://dx.doi.org/10.1515/zpch-2016-0824
Kovtunov K.V., Zhivonitko V.V., Skovpin I.V., Salnikov O.G., Koptyug I.V. // Catalytic Enhancement of NMR Sensitivity for Advanced Spectroscopic and Imaging Studies in Catalysis and Life Sciences // In: Magnetic Nanomaterials: Applications in Catalysis and Life Sciences, 2017, 142-171. ISBN: 978-1-78262-788-3; http://dx.doi.org/10.1039/9781788010375-00142
2016
D.B. Burueva, O.G. Salnikov, K.V. Kovtunov, A.S. Romanov, L.M. Kovtunova, A.K. Khudorozhkov, A.V. Bukhtiyarov, I.P. Prosvirin, V.I. Bukhtiyarov, I.V. Koptyug. Hydrogenation of unsaturated six-membered cyclic hydrocarbons studied by the parahydrogen-induced polarization technique, J. Phys. Chem. C, 120, 13541-13548 (2016); http://dx.doi.org/10.1021/acs.jpcc.6b03267
K.V. Kovtunov, A.S. Romanov, O.G. Salnikov, D.A. Barskiy, E.Y. Chekmenev, I.V. Koptyug. Gas phase UTE MRI of propane and propene, Tomography, 2, 49-55 (2016); http://dx.doi.org/10.18383/j.tom.2016.00112
V.V. Zhivonitko, K. Sorochkina, K. Chernichenko, B. Kotai, T. Foldes, I. Papai, V.-V. Telkki, T. Repo, I. Koptyug. Nuclear spin hyperpolarization with ansa-aminoboranes: a metal-free perspective for parahydrogen-induced polarization, Phys. Chem. Chem. Phys. (2016) , 40; http://dx.doi.org/10.1039/C6CP05211H
K.V. Kovtunov, D.A. Barskiy, R.V. Shchepin, O.G. Salnikov, I.P. Prosvirin, A.V. Bukhtiyarov, L.M. Kovtunova, V.I. Bukhtiyarov, I.V. Koptyug, E.Y. Chekmenev. Production of pure aqueous 13C-hyperpolarized acetate via heterogeneous parahydrogen-induced polarization, Chem. Eur. J. (2016), 22 (47); http://dx.doi.org/10.1002/chem.201603974
O.G. Salnikov, D.A. Barskiy, A.M. Coffey, K.V. Kovtunov, I.V. Kotyug, E.Y. Chekmenev. Efficient batch-mode parahydrogen-induced polarization of propane, ChemPhysChem (2016), 17 (21); http://dx.doi.org/10.1002/cphc.201600564
V.V. Zhivonitko, I.V. Skovpin, M. Crespo-Quesada, L. Kiwi-Minsker, I.V. Koptyug. Acetylene oligomerization over Pd nanoparticles with controlled shape: a parahydrogen-induced polarization study, J. Phys. Chem. C, 120, 4945-4953 (2016) ; http://dx.doi.org/10.1021/acs.jpcc.5b12391
K.V. Kovtunov, O.G. Salnikov, V.V. Zhivonitko, I.V. Skovpin, V.I. Bukhtiyarov, I.V. Koptyug. Catalysis and nuclear magnetic resonance signal enhancement with parahydrogen, Topics in Catalysis (2016), 59 (19-20), 1686-1699; http://dx.doi.org/10.1007/s11244-016-0688-6
D.A. Barskiy, A.N. Pravdivtsev, K.L. Ivanov, K.V. Kovtunov, I.V. Koptyug. Simple analytical model for signal amplification by reversible exchange (SABRE) process, Phys. Chem. Chem. Phys., 18, 89-93 (2016); http://dx.doi.org/10.1039/C5CP05134G
O.G. Salnikov, D.B. Burueva, E.Y. Gerasimov, A.V. Bukhtiyarov, A.K. Khudorozhkov, I.P. Prosvirin, L.M. Kovtunova, D.A. Barskiy, V.I. Bukhtiyarov, K.V. Kovtunov, I.V. Koptyug. The effect of oxidative and reductive treatments of titania-supported metal catalysts on the pairwise hydrogen addition to unsaturated hydrocarbons, Catal. Today (2016) , 283, 82-88; http://dx.doi.org/10.1016/j.cattod.2016.02.030
K.V. Kovtunov, D.A. Barskiy, O. Salnikov, R.V. Shchepin, A.M. Coffey, L. Kovtunova, V. Bukhtiyarov, I.V. Koptyug, E. Chekmenev. Toward production of pure 13C hyperpolarized metabolites using heterogeneous parahydrogen-induced polarization of ethyl [1-13C]acetate, RSC Adv., 6, 69728-69732 (2016); http://dx.doi.org/10.1039/C6RA15808K
B. Vuichoud, E. Canet, J. Milani, A. Bornet, D. Baudouin, L. Veyre, D. Gajan, L. Emsley, A. Lesage, C. Coperet, C. Thieuleux, G. Bodenhausen, I. Koptyug, S. Jannin. Hyperpolarization of frozen hydrocarbon gases by dynamic nuclear polarization at 1.2 K, J. Phys. Chem. Lett., 7, 3235-3239 (2016); http://dx.doi.org/10.1021/acs.jpclett.6b01345
D.A. Barskiy, O.G. Salnikov, R.V. Shchepin, M.A. Feldman, A.M. Coffey, K.V. Kovtunov, I.V. Koptyug, E.Y. Chekmenev. NMR SLIC Sensing of Hydrogenation Reactions Using Parahydrogen in Low Magnetic Fields, J. Phys. Chem. C, 120, 29098-29106 (2016); https://doi.org/10.1021/acs.jpcc.6b07555
2015
M.S. Krestina, O.B. Shevelev, I.V. Koptyug, L.A. Gerlinskaya, S.E. Peltek, A.E. Akulov. NMR metabolic profiling of the liver following administration of alcohol and the mushroom Ganoderma lucidum in rats, Vavilov J. Genet. Breed., 19, 499-504 (2015); http://dx.doi.org/10.18699/VJ15.067
O.G. Salnikov, D.B. Burueva, D.A. Barskiy, G.A. Bukhtiyarova, K.V. Kovtunov, I.V. Koptyug. A mechanistic study of thiophene hydrodesulfurization by the parahydrogen-induced polarization technique, ChemCatChem, 7, 3508-3512 (2015); http://dx.doi.org/10.1002/cctc.201500691
K.V. Kovtunov, D.A. Barskiy, O.G. Salnikov, D.B. Burueva, A.K. Khudorozhkov, A.V. Bukhtiyarov, I.P. Prosvirin, E.Y. Gerasimov, V.I. Bukhtiyarov, I.V. Koptyug. Strong metal-support interactions for palladium supported on TiO2 catalysts in the heterogeneous hydrogenation with parahydrogen, ChemCatChem, 7, 2581-2584 (2015); http://dx.doi.org/10.1002/cctc.201500618
S. Ahola, V.V. Zhivonitko, O. Mankinen, G. Zhang, A.M. Kantola, H.-Y. Chen, C. Hilty, I.V. Koptyug, V.-V. Telkki. Ultrafast multidimensional Laplace NMR for a rapid and sensitive chemical analysis, Nature Comm., 6, 8363 (2015); http://dx.doi.org/10.1038/ncomms9363
O.G. Salnikov, K.V. Kovtunov, I.V. Koptyug. Production of catalyst-free hyperpolarised ethanol aqueous solution via heterogeneous hydrogenation with parahydrogen, Sci. Rep., 5, 13930 (2015); http://dx.doi.org/10.1038/srep13930
A.S. Chubarov, O.D. Zakharova, O.A. Koval, A.V. Romaschenko, A.E. Akulov, E.L. Zavjalov, I.A. Razumov, I.V. Koptyug, D.G. Knorre, T.S. Godovikova. Design of protein homocystamides with enhanced tumor uptake properties for 19F magnetic resonance imaging, Bioorg. Med. Chem., 23, 6943-6954 (2015); http://dx.doi.org/10.1016/j.bmc.2015.09.043
V.V. Zhivonitko, I.V. Skovpin, I.V. Koptyug. Strong 31P nuclear spin hyperpolarization produced via reversible chemical interaction with parahydrogen, Chem. Commun., 51, 2506-2509 (2015); http://dx.doi.org/10.1039/C4CC08115C
A. Corma, O.G. Salnikov, D.A. Barskiy, K.V. Kovtunov, I.V. Koptyug. Single-atom gold catalysis in the context of developments in parahydrogen-induced polarization, Chem. Eur. J., 21, 7012-7015 (2015); http://dx.doi.org/10.1002/chem.201406664
D.A. Barskiy, O.G. Salnikov, K.V. Kovtunov, I.V. Koptyug. NMR signal enhancement for hyperpolarized fluids continuously generated in hydrogenation reactions with parahydrogen, J. Phys. Chem. A, 119, 996-1006 (2015); http://dx.doi.org/10.1021/jp510572d
2014
M.P. Moshkin, D.V. Petrovski, A.E. Akulov, A.V. Romaschenko, L.A. Gerlinskaya, M.I. Muchnaya, V.L. Ganimedov, A.S. Sadovsky, A.A. Savelov, I.V. Koptyug, S.Y. Troitsky, V.I. Bukhtiyarov, N.A. Kolchanov, R.Z. Sagdeyev, V.M. Fomin. Aerosol deposition in nasal passages of burrowing and ground rodents when breathing dust-laden air, Biol. Bull. Rev., 5, 36-45 (2015) (Zhurnal Obshchei Biologii, 2014, Vol. 75, No. 3, pp. 214-225); http://dx.doi.org/10.1134/S2079086415010065
A.E. Akulov, T.A. Alekhina, I.O, Meshkov, E.D. Petrovskii, O.I. Prokudina, I.V. Koptiug, A.A. Savelov, M.P. Moshkin. Selection for catatonic reaction in rats: a study of interstrain differences by magnetic resonance imaging, Zh. Vyssh. Nerv. Deiat. Im. I.P. Pavlova, 64, 439-447 (2014) (I.P. Pavlov Journal of Higher Nervous Activity; in Russian)
K.V. Kovtunov, M.L. Truong, D.A. Barskiy, I.V. Koptyug, A.M. Coffey, K.W. Waddell, E.Y. Chekmenev. Long-lived spin states for low-field hyperpolarized gas MRI, Chem. Eur. J., 20, 14629-14632 (2014); http://dx.doi.org/10.1002/chem.201405063
V.P. Ananikov, L.L. Khemchyan, Yu.V.. Ivanova, V.I. Bukhtiyarov, A.M. Sorokin, I.P. Prosvirin, S.Z. Vatsadze, A.V. Medved'ko, V.N. Nuriev, A.D. Dilman, V.V. Levin, I.V. Koptyug, K.V. Kovtunov, V.V. Zhivonitko, V.A. Likholobov, A.V. Romanenko, P.A. Simonov, V.G. Nenajdenko, O.I. Shmatova, V.M. Muzalevskiy, M.S. Nechaev, A.F. Asachenko, O.S. Morozov, P.B. Dzhevakov, S.N. Osipov, D.V. Vorobyeva, M.A. Topchiy, M.A. Zotova, S.A. Ponomarenko, O.V. Borshchev, Y.N. Luponosov, A.A. Rempel, A.A. Valeeva, A.Y. Stakheev, O.V. Turova, I.S. Mashkovsky, S.V. Sysolyatin, V.V. Malykhin, G.A. Bukhtiyarova, A.O. Terent'ev, I.B. Krylov. Development of new methods in modern selective organic synthesis: preparation of functionalized molecules with atomic precision, Russ. Chem. Rev., 83, 885-985 (2014); http://dx.doi.org/10.1070/RC2014v083n10ABEH004471
K.V. Kovtunov, D.A. Barskiy, A.M. Coffey, M.L. Truong, O.G. Salnikov, A.K. Khudorozhkov, E.A. Inozemtseva, I.P. Prosvirin, V.I. Bukhtiyarov, K.W. Waddell, E.Y. Chekmenev, I.V. Koptyug. High-resolution 3D proton MRI of hyperpolarized gas enabled by parahydrogen and Rh/TiO2 heterogeneous catalyst, Chem. Eur. J., 20, 11636-11639 (2014); http://dx.doi.org/10.1002/chem.201403604
D.A. Barskiy, K.V. Kovtunov, I.V. Koptyug, P. He, K.A. Groome, Q.A. Best, F. Shi, B.M. Goodson, R.V. Shchepin, M.L. Truong, A.M. Coffey, K.W. Waddell, E.Y. Chekmenev. In situ and ex situ low-field NMR spectroscopy and MRI endowed by SABRE hyperpolarization, ChemPhysChem, 15, 4100-4107 (2014); http://dx.doi.org/10.1002/cphc.201402607
I.V. Koptyug. "Magnetic resonance imaging methods in heterogeneous catalysis", in: Spectroscopic Properties of Inorganic and Organometallic Compounds, R. Douthwaite, S. Duckett, J. Yarwood, eds. 2014, Royal Society of Chemistry:Cambridge, 1-42; http://dx.doi.org/10.1039/9781782621485-00001
V.V. Zhivonitko, K.V. Kovtunov, I.V. Skovpin, D.A. Barskiy, O.G. Salnikov, I.V. Koptyug. "Catalytically enhanced NMR of heterogeneously catalyzed hydrogenations, Computational and experimental tools", in: Understanding organometallic reaction mechanisms and catalysis, V.P. Ananikov, eds. 2014, Wiley-VCH Verlag GmbH & Co. KGaA, 145-186; http://dx.doi.org/10.1002/9783527678211
M.P. Moshkin, A.E. Akulov, D.V. Petrovski, O.V. Saik, E.D. Petrovskiy, A.A. Savelov, I.V. Koptyug. Proton magnetic resonance spectroscopy of brain metabolic shifts induced by acute administration of 2-deoxy-d-glucose and lipopolysaccharides, NMR Biomed., 27, 399-405 (2014); http://dx.doi.org/10.1002/nbm.3074
V.-V. Telkki, V.V. Zhivonitko, A. Selent, G. Scotti, J. Leppaniemi, S. Franssila, I.V. Koptyug. Lab-on-a-chip reactor imaging with unprecedented chemical resolution by Hadamard-encoded remote detection NMR, Angew. Chem. Int. Ed., 53, 11289-11293 (2014); http://dx.doi.org/10.1002/anie.201405681
D.A. Barskiy, K.V. Kovtunov, I.V. Koptyug, P. He, K.A. Groome, Q.A. Best, F. Shi, B.M. Goodson, R.V. Shchepin, A.M. Coffey, K.W. Waddell, E.Y. Chekmenev. The feasibility of formation and kinetics of NMR signal amplification by reversible exchange (SABRE) at high magnetic field (9.4 T), J. Am. Chem. Soc., 136, 3322-3325 (2014); http://dx.doi.org/10.1021/ja501052p
K.V. Kovtunov, D.A. Barskiy, R.V. Shchepin, A.M. Coffey, K.W. Waddell, I.V. Koptyug, E.Y. Chekmenev. Demonstration of heterogeneous parahydrogen induced polarization using hyperpolarized agent migration from dissolved Rh(I) complex to gas phase, Anal. Chem., 86, 6192-6196 (2014); http://dx.doi.org/10.1021/ac5013859
O.G. Salnikov, D.A. Barskiy, D.B. Burueva, Y.K. Gulyaeva, B.S. Balzhinimaev, K.V. Kovtunov, I.V. Koptyug. Evaluation of activation energies for pairwise and non-pairwise hydrogen addition to propyne over Pd/aluminosilicate fiberglass catalyst by parahydrogen-induced polarization (PHIP), Appl. Magn. Reson., 45, 1051-1061 (2014); http://dx.doi.org/10.1007/s00723-014-0586-7
A.M. Coffey, K.V. Kovtunov, D.A. Barskiy, I.V. Koptyug, R.V. Shchepin, K.W. Waddell, P. He, K.A. Groome, Q.A. Best, F. Shi, B.M. Goodson, E.Y. Chekmenev. High-resolution low-field molecular magnetic resonance imaging of hyperpolarized liquids, Anal. Chem., 86, 9042-9049 (2014); http://dx.doi.org/10.1021/ac501638p
O.G. Salnikov, K.V. Kovtunov, D.A. Barskiy, A.K. Khudorozhkov, E.A. Inozemtseva, I.P. Prosvirin, V.I. Bukhtiyarov, I.V. Koptyug. Evaluation of the mechanism of heterogeneous hydrogenation of alpha,beta-unsaturated carbonyl compounds via pairwise hydrogen addition, ACS Catal., 4, 2022-2028 (2014); http://dx.doi.org/10.1021/cs500426a
K.V. Kovtunov, M.L Truong, D.A Barskiy, O.G. Salnikov, V.I. Bukhtiyarov, A.M Coffey, K.W Waddell, I.V. Koptyug, E.Y Chekmenev. Propane-d6 heterogeneously hyperpolarized by parahydrogen, J. Phys. Chem. C, 118, 28234-28243 (2014); http://dx.doi.org/10.1021/jp508719n
M.P. Moshkin, D.V. Petrovski, A.E. Akulov, A.V. Romashchenko, L.A. Gerlinskaya, V.L. Ganimedov, M.I. Muchnaya, A.S. Sadovsky, I.V. Koptyug, A.A. Savelov, S.Y. Troitsky, Y.M. Moshkn, V.I. Bukhtiyarov, N.A. Kolchanov, R.Z. Sagdeev, V.M. Fomin. Nasal aerodynamics protects brain and lung from inhaled dust in subterranean diggers, Ellobius talpinus, Proc. R. Soc. B, 281, 20140919 (2014); http://dx.doi.org/10.1098/rspb.2014.0919
M.L Truong, F. Shi, P. He, B. Yuan, K.N Plunkett, A.M Coffey, R.V Shchepin, D.A Barskiy, K.V. Kovtunov, I.V. Koptyug, K.W Waddell, B.M. Goodson, E.Y Chekmenev. Irreversible catalyst activation enables hyperpolarization and water solubility for NMR signal amplification by reversible exchange, J. Phys. Chem. B, 118, 13882-13889 (2014); http://dx.doi.org/10.1021/jp510825b
K.V. Kovtunov, D.A. Barskiy, O.G. Salnikov, A.K. Khudorozhkov, V.I. Bukhtiyarov, I.P. Prosvirin, I.V. Koptyug. Parahydrogen-induced polarization (PHIP) in heterogeneous hydrogenations over bulk metals and metal oxides, Chem. Commun., 50, 875-878 (2014); http://dx.doi.org/10.1039/C3CC44939D
V.V. Zhivonitko, V.-V. Telkki, K. Chernichenko, T.J.
